Uncoupling of PUMA Expression and Apoptosis Contributes to Functional Heterogeneity in Renal Cell Carcinoma — Prognostic and Translational Implications()

Renal cell carcinoma (RCC) is characterized by a profound disruption of proapoptotic signaling networks leading to chemo- and radioresistance. A key mediator of DNA damage-induced apoptosis is the BH3-only protein PUMA. Given its central role in proapoptotic signaling, we analyzed a series of more t...

詳細記述

保存先:
書誌詳細
出版年:Transl Oncol
主要な著者: Zhou, Xiaoguang, Li, Jielin, Marx, Christina, Tolstov, Yanis, Rauch, Geraldine, Herpel, Esther, Macher-Goeppinger, Stephan, Roth, Wilfried, Grüllich, Carsten, Pahernik, Sascha, Hohenfellner, Markus, Duensing, Stefan
フォーマット: Artigo
言語:Inglês
出版事項: Neoplasia Press 2015
主題:
Original article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700292/
https://ncbi.nlm.nih.gov/pubmed/26692529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2015.11.003
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