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Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways
A hallmark feature of amyotrophic lateral sclerosis (ALS) is that symptoms appear to spread along neuroanatomical pathways to engulf the motor nervous system, suggesting a propagative toxic entity could be involved in disease pathogenesis. Evidence for such a propagative entity emerged recently in s...
Guardat en:
| Publicat a: | Acta Neuropathol |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4699876/ https://ncbi.nlm.nih.gov/pubmed/26650262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1514-0 |
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