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Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry

Phosphorylation is an important mechanism by which Gli proteins are regulated. When the Hedgehog (Hh) pathway is activated, multiple serine and threonine residues of Gli2 are dephosphorylated, while at least one residue undergoes phosphorylation. These changes in phosphorylation have functional rele...

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Bibliografski detalji
Izdano u:Methods Mol Biol
Glavni autori: Ahrends, Robert, Niewiadomski, Pawel, Teruel, Mary N., Rohatgi, Rajat
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699800/
https://ncbi.nlm.nih.gov/pubmed/26179043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2772-2_10
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