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Protein turnover measurement using selected reaction monitoring-mass spectrometry (SRM-MS)

Protein turnover represents an important mechanism in the functioning of cells, with deregulated synthesis and degradation of proteins implicated in many diseased states. Therefore, proteomics strategies to measure turnover rates with high confidence are of vital importance to understanding many bio...

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Detalhes bibliográficos
Publicado no:Philos Trans A Math Phys Eng Sci
Main Authors: Holman, Stephen W., Hammond, Dean E., Simpson, Deborah M., Waters, John, Hurst, Jane L., Beynon, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5031629/
https://ncbi.nlm.nih.gov/pubmed/27644981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsta.2015.0362
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