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Effect of Collision Energy Optimization on the Measurement of Peptides by Selected Reaction Monitoring (SRM) Mass Spectrometry

Proteomics experiments based on Selected Reaction Monitoring (SRM, also referred to as Multiple Reaction Monitoring or MRM) are being used to target large numbers of protein candidates in complex mixtures. At present, instrument parameters are often optimized for each peptide, a time and resource in...

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Detalhes bibliográficos
Main Authors: MacLean, Brendan, Tomazela, Daniela M., Abbatiello, Susan E., Zhang, Shucha, Whiteaker, Jeffrey R., Paulovich, Amanda G., Carr, Steven A., MacCoss, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005404/
https://ncbi.nlm.nih.gov/pubmed/21090646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac102179j
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