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Expediting the Development of Targeted SRM Assays: Using Data from Shotgun Proteomics to Automate Method Development

Selected reaction monitoring (SRM) is a powerful tandem mass spectrometry method that can be used to monitor target peptides within a complex protein digest. The specificity and sensitivity of the approach, as well as its capability to multiplex the measurement of many analytes in parallel, has made...

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Autors principals: Prakash, Amol, Tomazela, Daniela M., Frewen, Barbara, MacLean, Brendan, Merrihew, Gennifer, Peterman, Scott, MacCoss, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743471/
https://ncbi.nlm.nih.gov/pubmed/19326923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr801028b
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