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The effect of leptin replacement on sleep-disordered breathing in the leptin-deficient ob/ob mouse
Obese leptin-deficient (ob/ob) mice demonstrate defects in upper airway structural and neuromuscular control. We hypothesized that these defects predispose to upper airway obstruction during sleep, and improve with leptin administration. High-fidelity polysomnographic recordings were conducted to ch...
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| 出版年: | J Appl Physiol (1985) |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698442/ https://ncbi.nlm.nih.gov/pubmed/26472867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00494.2015 |
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