Localizing Effects of Leptin on Upper Airway and Respiratory Control during Sleep

STUDY OBJECTIVES: Obesity hypoventilation and obstructive sleep apnea are common complications of obesity linked to defects in respiratory pump and upper airway neural control. Leptin-deficient ob/ob mice have impaired ventilatory control and inspiratory flow limitation during sleep, which are both...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Yao, Qiaoling, Pho, Huy, Kirkness, Jason, Ladenheim, Ellen E., Bi, Sheng, Moran, Timothy H., Fuller, David D., Schwartz, Alan R., Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2016
Assuntos:
Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835308/
https://ncbi.nlm.nih.gov/pubmed/26951402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5762
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