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Effects of leptin and obesity on the upper airway function

Obesity is associated with alterations in upper airway collapsibility during sleep. Obese, leptin-deficient mice demonstrate blunted ventilatory control, leading us to hypothesize that (1) obesity and leptin deficiency would predispose to worsening neuromechanical upper airway function and that (2)...

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Detalhes bibliográficos
Main Authors: Polotsky, Mikhael, Elsayed-Ahmed, Ahmed S., Pichard, Luis, Harris, Christopher C., Smith, Philip L., Schneider, Hartmut, Kirkness, Jason P., Polotsky, Vsevolod, Schwartz, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365404/
https://ncbi.nlm.nih.gov/pubmed/22345430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01222.2011
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