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CONFORMATIONAL SEARCHES ELUCIDATE EFFECTS OF STEREOCHEMISTRY ON STRUCTURES OF DEOXYADENOSINE COVALENTLY BOUND TO TUMORIGENIC METABOLITES OF BENZO[C] PHENANTHRENE
Remarkably different conformations can result when DNA binds with stereoisomeric compounds containing differing absolute configurations of substituents about chiral carbon atoms. Furthermore, the biochemical functions of covalent adducts with DNA are strongly affected by the stereochemistry of the l...
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| Publicado no: | Front Biosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4697942/ https://ncbi.nlm.nih.gov/pubmed/15353316 |
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