Synthesis and Antileukemic Activities of C1-C10-Modified Parthenolide Analogues

Parthenolide (PTL) is a sesquiterpene lactone natural product with anti-proliferative activity to cancer cells. Selective eradication of leukemic stem cells (LSCs) over healthy hematopoietic stem cells (HSCs) by PTL has been demonstrated in previous studies, which suggests PTL and related molecules...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Med Chem
Egile Nagusiak: Kempema, Aaron M., Widen, John C., Hexum, Joseph K., Andrews, Timothy E., Wang, Dan, Rathe, Susan K., Meece, Frederick A., Noble, Klara E., Sachs, Zohar, Largaespada, David A., Harki, Daniel A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697833/
https://ncbi.nlm.nih.gov/pubmed/26088334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.05.037
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