Targeting NF-κB p65 with a Helenalin Inspired Bis-electrophile

Por Widen, John C., Kempema, Aaron M., Villalta, Peter W., Harki, Daniel A.
Publicado no ACS Chem Biol (2016)

EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer

Por Brand, Lucas J., Olson, Margaret E., Ravindranathan, Preethi, Guo, Hong, Kempema, Aaron M., Andrews, Timothy E., Chen, Xiaoli, Raj, Ganesh V., Harki, Daniel A., Dehm, Scott M.
Publicado no Oncotarget (2015)

Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle

Por Kerr, Jaclyn P., Robison, Patrick, Shi, Guoli, Bogush, Alexey I., Kempema, Aaron M., Hexum, Joseph K., Becerra, Natalia, Harki, Daniel A., Martin, Stuart S., Raiteri, Roberto, Prosser, Benjamin L., Ward, Christopher W.
Publicado no Nat Commun (2015)

Synthesis and Antileukemic Activities of C1-C10-Modified Parthenolide Analogues

Por Kempema, Aaron M., Widen, John C., Hexum, Joseph K., Andrews, Timothy E., Wang, Dan, Rathe, Susan K., Meece, Frederick A., Noble, Klara E., Sachs, Zohar, Largaespada, David A., Harki, Daniel A.
Publicado no Bioorg Med Chem (2015)