EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer

The androgen receptor (AR) is a driver of prostate cancer (PCa) cell growth and disease progression. Therapies for advanced PCa exploit AR dependence by blocking the production or action of androgens, but these interventions inevitably fail via multiple mechanisms including mutation or deletion of t...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Brand, Lucas J., Olson, Margaret E., Ravindranathan, Preethi, Guo, Hong, Kempema, Aaron M., Andrews, Timothy E., Chen, Xiaoli, Raj, Ganesh V., Harki, Daniel A., Dehm, Scott M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414155/
https://ncbi.nlm.nih.gov/pubmed/25669987
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