EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer

The androgen receptor (AR) is a driver of prostate cancer (PCa) cell growth and disease progression. Therapies for advanced PCa exploit AR dependence by blocking the production or action of androgens, but these interventions inevitably fail via multiple mechanisms including mutation or deletion of t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Brand, Lucas J., Olson, Margaret E., Ravindranathan, Preethi, Guo, Hong, Kempema, Aaron M., Andrews, Timothy E., Chen, Xiaoli, Raj, Ganesh V., Harki, Daniel A., Dehm, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414155/
https://ncbi.nlm.nih.gov/pubmed/25669987
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