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Central Role for PELP1 in Nonandrogenic Activation of the Androgen Receptor in Prostate Cancer

The ability of 17β-estradiol (E2) to regulate the proliferation of prostate cancer (PCa) cells in the absence of androgen is poorly understood. Here, we show the predominant estrogen receptor (ER) isoform expressed in PCa specimens and cell lines is ERβ. Our data indicate that E2 induces the formati...

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Detalhes bibliográficos
Publicado no:Mol Endocrinol
Main Authors: Yang, Lin, Ravindranathan, Preethi, Ramanan, Meera, Kapur, Payal, Hammes, Stephen R., Hsieh, Jer-Tsong, Raj, Ganesh V.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417135/
https://ncbi.nlm.nih.gov/pubmed/22403175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1101
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