Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer

The transcription factor E-twenty-six related gene (ERG), which is overexpressed through gene fusion with the androgen-responsive gene transmembrane protease, serine 2 (TMPRSS2) in ∼40% of prostate tumors, is a key driver of prostate carcinogenesis. Ablation of ERG would disrupt a key oncogenic tran...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Wang, Shan, Kollipara, Rahul K., Srivastava, Nishi, Li, Rui, Ravindranathan, Preethi, Hernandez, Elizabeth, Freeman, Eva, Humphries, Caroline G., Kapur, Payal, Lotan, Yair, Fazli, Ladan, Gleave, Martin E., Plymate, Stephen R., Raj, Ganesh V., Hsieh, Jer-Tsong, Kittler, Ralf
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3964108/
https://ncbi.nlm.nih.gov/pubmed/24591637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322198111
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires