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Oncogenic activation of ERG: A predominant mechanism in prostate cancer

Prevalent gene fusions involving regulatory sequences of the androgen receptor (AR) regulated genes (primarily TMPRSS2) and protein coding sequences of nuclear transcription factors of the ETS gene family (predominantly ERG) result in unscheduled androgen dependent ERG expression in prostate cancer...

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Bibliografiske detaljer
Main Authors: Sreenath, Taduru L, Dobi, Albert, Petrovics, Gyorgy, Srivastava, Shiv
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3263025/
https://ncbi.nlm.nih.gov/pubmed/22279422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1477-3163.91122
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