Central Role for PELP1 in Nonandrogenic Activation of the Androgen Receptor in Prostate Cancer

The ability of 17β-estradiol (E2) to regulate the proliferation of prostate cancer (PCa) cells in the absence of androgen is poorly understood. Here, we show the predominant estrogen receptor (ER) isoform expressed in PCa specimens and cell lines is ERβ. Our data indicate that E2 induces the formati...

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Dettagli Bibliografici
Pubblicato in:Mol Endocrinol
Autori principali: Yang, Lin, Ravindranathan, Preethi, Ramanan, Meera, Kapur, Payal, Hammes, Stephen R., Hsieh, Jer-Tsong, Raj, Ganesh V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2012
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417135/
https://ncbi.nlm.nih.gov/pubmed/22403175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1101
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