Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle

In striated muscle, X-ROS is the mechanotransduction pathway by which mechanical stress transduced by the microtubule network elicits reactive oxygen species. X-ROS tunes Ca(2+) signalling in healthy muscle, but in diseases such as Duchenne muscular dystrophy (DMD), microtubule alterations drive ele...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Kerr, Jaclyn P., Robison, Patrick, Shi, Guoli, Bogush, Alexey I., Kempema, Aaron M., Hexum, Joseph K., Becerra, Natalia, Harki, Daniel A., Martin, Stuart S., Raiteri, Roberto, Prosser, Benjamin L., Ward, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633818/
https://ncbi.nlm.nih.gov/pubmed/26446751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9526
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