Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

Mitochondria are highly dynamic subcellular organelles participating in many signaling pathways such as antiviral innate immunity and cell death cascades. Here we found that mitochondrial fusion was impaired in dengue virus (DENV) infected cells. Two mitofusins (MFN1 and MFN2), which mediate mitocho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Yu, Chia-Yi, Liang, Jian-Jong, Li, Jin-Kun, Lee, Yi-Ling, Chang, Bi-Lan, Su, Chan-I, Huang, Wei-Jheng, Lai, Michael M. C., Lin, Yi-Ling
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696832/
https://ncbi.nlm.nih.gov/pubmed/26717518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005350
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