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Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins

Mitochondria are highly dynamic subcellular organelles participating in many signaling pathways such as antiviral innate immunity and cell death cascades. Here we found that mitochondrial fusion was impaired in dengue virus (DENV) infected cells. Two mitofusins (MFN1 and MFN2), which mediate mitocho...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Yu, Chia-Yi, Liang, Jian-Jong, Li, Jin-Kun, Lee, Yi-Ling, Chang, Bi-Lan, Su, Chan-I, Huang, Wei-Jheng, Lai, Michael M. C., Lin, Yi-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696832/
https://ncbi.nlm.nih.gov/pubmed/26717518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005350
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