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Mitofusins and the mitochondrial permeability transition: the potential downside of mitochondrial fusion
Mitofusins (Mfn-1 and Mfn-2) are transmembrane proteins that bind and hydrolyze guanosine 5′-triphosphate to bring about the merging of adjacent mitochondrial membranes. This event is necessary for mitochondrial fusion, a biological process that is critical for organelle function. The broad effects...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3423162/ https://ncbi.nlm.nih.gov/pubmed/22636681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00185.2012 |
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