TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response

Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this pathway is unclear. Unlike kinases, the activity and specificity of serine/threonine phosphatases is governed largely by their associated pr...

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Vydáno v:PLoS One
Hlavní autoři: Rosales, Kimberly Romero, Reid, Michael A., Yang, Ying, Tran, Thai Q., Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696667/
https://ncbi.nlm.nih.gov/pubmed/26717153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145938
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