TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response

Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this pathway is unclear. Unlike kinases, the activity and specificity of serine/threonine phosphatases is governed largely by their associated pr...

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Publicat a:PLoS One
Autors principals: Rosales, Kimberly Romero, Reid, Michael A., Yang, Ying, Tran, Thai Q., Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696667/
https://ncbi.nlm.nih.gov/pubmed/26717153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145938
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