TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response

Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this pathway is unclear. Unlike kinases, the activity and specificity of serine/threonine phosphatases is governed largely by their associated pr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rosales, Kimberly Romero, Reid, Michael A., Yang, Ying, Tran, Thai Q., Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696667/
https://ncbi.nlm.nih.gov/pubmed/26717153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145938
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