TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response

Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this pathway is unclear. Unlike kinases, the activity and specificity of serine/threonine phosphatases is governed largely by their associated pr...

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Publicado en:PLoS One
Autores principales: Rosales, Kimberly Romero, Reid, Michael A., Yang, Ying, Tran, Thai Q., Wang, Wen-I, Lowman, Xazmin, Pan, Min, Kong, Mei
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696667/
https://ncbi.nlm.nih.gov/pubmed/26717153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145938
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