Hyperglycemia-induced metabolic compensation inhibits metformin sensitivity in ovarian cancer

Increasing interest in repurposing the diabetic medication metformin for cancer treatment has raised important questions about the translation of promising preclinical findings to therapeutic efficacy, especially in non-diabetic patients. A significant limitation of the findings to date is the use o...

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Vydáno v:Oncotarget
Hlavní autoři: Litchfield, Lacey M., Mukherjee, Abir, Eckert, Mark A., Johnson, Alyssa, Mills, Kathryn A., Pan, Shawn, Shridhar, Viji, Lengyel, Ernst, Romero, Iris L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695136/
https://ncbi.nlm.nih.gov/pubmed/26172303
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