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V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy
In addition to being a master regulator of cell cycle progression, E2F1 regulates other associated biological processes, including growth and malignancy. Here, we uncover a regulatory network linking E2F1 to lysosomal trafficking and mTORC1 signaling that involves v-ATPase regulation. By immunofluor...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695044/ https://ncbi.nlm.nih.gov/pubmed/26356814 |
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