IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of age‐related cog...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Toth, Peter, Tarantini, Stefano, Ashpole, Nicole M., Tucsek, Zsuzsanna, Milne, Ginger L., Valcarcel‐Ares, Noa M., Menyhart, Akos, Farkas, Eszter, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693458/
https://ncbi.nlm.nih.gov/pubmed/26172407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12372
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