IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of moment‐to‐moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of age‐related cog...

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Bibliografiska uppgifter
I publikationen:Aging Cell
Huvudupphovsmän: Toth, Peter, Tarantini, Stefano, Ashpole, Nicole M., Tucsek, Zsuzsanna, Milne, Ginger L., Valcarcel‐Ares, Noa M., Menyhart, Akos, Farkas, Eszter, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2015
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693458/
https://ncbi.nlm.nih.gov/pubmed/26172407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12372
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