Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

FEN1 has key roles in Okazaki fragment maturation during replication, long patch base excision repair, rescue of stalled replication forks, maintenance of telomere stability and apoptosis. FEN1 may be dysregulated in breast and ovarian cancers and have clinicopathological significance in patients. W...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Abdel-Fatah, Tarek M.A., Russell, Roslin, Albarakati, Nada, Maloney, David J., Dorjsuren, Dorjbal, Rueda, Oscar M., Moseley, Paul, Mohan, Vivek, Sun, Hongmao, Abbotts, Rachel, Mukherjee, Abhik, Agarwal, Devika, Illuzzi, Jennifer L., Jadhav, Ajit, Simeonov, Anton, Ball, Graham, Chan, Stephen, Caldas, Carlos, Ellis, Ian O., Wilson, David M., Madhusudan, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690463/
https://ncbi.nlm.nih.gov/pubmed/24880630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.04.009
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