EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer

The EglN2/PHD1 prolyl hydroxylase is an important oxygen sensor contributing to breast tumorigenesis. Emerging studies suggest that there is functional cross talk between oxygen sensing and mitochondrial function, both of which play an essential role for sustained tumor growth. However, the potentia...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Zhang, Jing, Wang, Chengyang, Chen, Xi, Takada, Mamoru, Fan, Cheng, Zheng, Xingnan, Wen, Haitao, Liu, Yong, Wang, Chenguang, Pestell, Richard G, Aird, Katherine M, Kaelin, William G, Liu, Xiaole Shirley, Zhang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687683/
https://ncbi.nlm.nih.gov/pubmed/26492917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591437
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