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Design and Synthesis of Norendoxifen Analogues with Dual Aromatase Inhibitory and Estrogen Receptor Modulatory Activities

Both selective estrogen receptor modulators and aromatase inhibitors are widely used for the treatment of breast cancer. Compounds with both aromatase inhibitory and estrogen receptor modulatory activities could have special advantages for treatment of breast cancer. Our previous efforts led to the...

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Podrobná bibliografie
Vydáno v:J Med Chem
Hlavní autoři: Lv, Wei, Liu, Jinzhong, Skaar, Todd C., Flockhart, David A., Cushman, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687028/
https://ncbi.nlm.nih.gov/pubmed/25751283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501218e
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