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Complementary annealing mediated by exonuclease: a method for seamless cloning and conditioning site-directed mutagenesis

Traditional cut-paste DNA cloning is often limited by the availability of restriction enzyme sites. Here, we described the complementary annealing mediated by exonuclease (CAME), in which the insert or vector fragment is amplified to carry sequences complementary to the other, and both fragments are...

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Detalhes bibliográficos
Publicado no:Biotechnol Biotechnol Equip
Main Authors: Sun, Shuhui, Huang, Hao, Qi, Yingchuan Billy, Qiu, Mengsheng, Dai, Zhong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686905/
https://ncbi.nlm.nih.gov/pubmed/26740790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13102818.2014.988094
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