A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis

Mammalian fetal development is easily disrupted by exogenous agents, making it essential to test new drug candidates for embryotoxicity and teratogenicity. To standardize the testing of drugs that might be used to treat pregnant women, the U.S. Food and Drug Administration (FDA) formulated special g...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Yu, Ruoxing, Miyamura, Norio, Okamoto-Uchida, Yoshimi, Arima, Norie, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686177/
https://ncbi.nlm.nih.gov/pubmed/26682887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145286
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