Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models

BACKGROUND: Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and poor patient prognosis. We have previously established an E-cadherin/p53 double conditional knockout (DCKO) mouse line as the first genetically engineered one, which morphologically and molecularly recapitulates hum...

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Publicat a:Br J Cancer
Autors principals: Shimada, Shu, Akiyama, Yoshimitsu, Mogushi, Kaoru, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Nagasaki, Hiromi, Fukamachi, Hiroshi, Yuasa, Yasuhito, Tanaka, Shinji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931092/
https://ncbi.nlm.nih.gov/pubmed/29527007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0008-y
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