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DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells

Twist1 overexpression is frequently observed in various cancers including gastric cancer (GC). Although DNA methylation of the Twist1 gene has been reported in cancer cells, the mechanisms underlying transcriptional activation remain uncertain. In this study, we first examined epigenetic alterations...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sakamoto, Ayuna, Akiyama, Yoshimitsu, Shimada, Shu, Zhu, Wei-Guo, Yuasa, Yasuhito, Tanaka, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687923/
https://ncbi.nlm.nih.gov/pubmed/26695186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145630
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