A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs on Early Embryogenesis

Mammalian fetal development is easily disrupted by exogenous agents, making it essential to test new drug candidates for embryotoxicity and teratogenicity. To standardize the testing of drugs that might be used to treat pregnant women, the U.S. Food and Drug Administration (FDA) formulated special g...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Ruoxing, Miyamura, Norio, Okamoto-Uchida, Yoshimi, Arima, Norie, Ishigami-Yuasa, Mari, Kagechika, Hiroyuki, Nishina, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686177/
https://ncbi.nlm.nih.gov/pubmed/26682887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145286
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