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Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.

The human epsilon-globin gene undergoes dramatic changes in transcriptional activity during development, but the molecular factors that control its high expression in the embryo and its complete repression at 6-8 weeks of gestation are unknown. Although a putative silencer has been identified, the a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Gumucio, D L, Shelton, D A, Bailey, W J, Slightom, J L, Goodman, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6018
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