Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.

Effective gene therapy constructs based on retrovirus or adeno-associated virus vectors will require regulatory elements that direct expression of genes transduced at single copy. Most beta-globin constructs designed for therapy of beta-thalassemias are regulated by the 5'HS2 component of the l...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Ellis, J, Pasceri, P, Tan-Un, K C, Wu, X, Harper, A, Fraser, P, Grosveld, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC146564/
https://ncbi.nlm.nih.gov/pubmed/9092642
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