Evaluation of beta-globin gene therapy constructs in single copy transgenic mice.
Effective gene therapy constructs based on retrovirus or adeno-associated virus vectors will require regulatory elements that direct expression of genes transduced at single copy. Most beta-globin constructs designed for therapy of beta-thalassemias are regulated by the 5'HS2 component of the locus...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC146564/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9092642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/25.6.1296 |
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