Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.

The human epsilon-globin gene undergoes dramatic changes in transcriptional activity during development, but the molecular factors that control its high expression in the embryo and its complete repression at 6-8 weeks of gestation are unknown. Although a putative silencer has been identified, the a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gumucio, D L, Shelton, D A, Bailey, W J, Slightom, J L, Goodman, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6018
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