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Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.
The human epsilon-globin gene undergoes dramatic changes in transcriptional activity during development, but the molecular factors that control its high expression in the embryo and its complete repression at 6-8 weeks of gestation are unknown. Although a putative silencer has been identified, the a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC46858/ https://ncbi.nlm.nih.gov/pubmed/8327477 |
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