Phylogenetic footprinting reveals unexpected complexity in trans factor binding upstream from the epsilon-globin gene.
The human epsilon-globin gene undergoes dramatic changes in transcriptional activity during development, but the molecular factors that control its high expression in the embryo and its complete repression at 6-8 weeks of gestation are unknown. Although a putative silencer has been identified, the a...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Proc Natl Acad Sci U S A |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
1993
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6018 |
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