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A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-immunization Protection against Inhaled Anthrax in Monkeys()

Nanoparticulate delivery systems for vaccine adjuvants, designed to enhance targeting of secondary lymphoid organs and activation of APCs, have shown substantial promise for enhanced immunopotentiation. We investigated the adjuvant activity of synthetic oligonucleotides containing CpG-rich motifs (C...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Kachura, Melissa A., Hickle, Colin, Kell, Sariah A., Sathe, Atul, Calacsan, Carlo, Kiwan, Radwan, Hall, Brian, Milley, Robert, Ott, Gary, Coffman, Robert L., Kanzler, Holger, Campbell, John D.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684989/
https://ncbi.nlm.nih.gov/pubmed/26608924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501903
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