CpG Oligodeoxynucleotides Adsorbed onto Polylactide-Co-Glycolide Microparticles Improve the Immunogenicity and Protective Activity of the Licensed Anthrax Vaccine

To reduce the biothreat posed by anthrax, efforts are under way to improve the protection afforded by vaccination. This work examines the ability of immunostimulatory CpG oligodeoxynucleotides (ODN) adsorbed onto cationic polylactide-co-glycolide (PLG) microparticles (CpG ODN-PLG) to accelerate and...

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Detalhes bibliográficos
Main Authors: Xie, Hang, Gursel, Ihsan, Ivins, Bruce E., Singh, Manmohan, O'Hagan, Derek T., Ulmer, Jeffrey B., Klinman, Dennis M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547063/
https://ncbi.nlm.nih.gov/pubmed/15664922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.828-833.2005
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