A limited CpG-containing oligodeoxynucleotide therapy regimen induces sustained suppression of allergic airway inflammation in mice

BACKGROUND: CpG-containing oligodeoxynucleotides (CpG-ODN) are potent inhibitors of Th2-mediated allergic airway disease in sensitized mice challenged with allergen. A single treatment has transient effects but a limited series of treatments has potential to achieve clinically meaningful sustained i...

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Bibliografische gegevens
Gepubliceerd in:Thorax
Hoofdauteurs: Campbell, John D., Kell, Sariah A., Kozy, Heather M., Lum, Jeremy A., Sweetwood, Rosemary, Chu, Mabel, Cunningham, Cameron R., Salamon, Hugh, Lloyd, Clare M., Coffman, Robert L., Hessel, Edith M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4558941/
https://ncbi.nlm.nih.gov/pubmed/24464743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2013-204605
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