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CpG oligodeoxynucleotides as immunotherapy in cancer

Preclinical and early clinical trials indicate synthetic oligodeoxynucleotides containing unmethylated CG dinucleotides (CpG ODN) have potent immunostimulatory effects and can enhance the anti-cancer activity of a variety of cancer treatments. Synergy between CpG ODN and monoclonal antibodies has be...

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Détails bibliographiques
Auteurs principaux: Jahrsdörfer, Bernd, Weiner, George J.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390897/
https://ncbi.nlm.nih.gov/pubmed/19255607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.uct.2007.11.003
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