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CpG oligodeoxynucleotides as mucosal adjuvants
Bacterial DNA comprising palindromic sequences and containing unmethylated CpG is recognized by toll-like receptor 9 of plasmacytoid dendritic cells (pDCs) and induces the production of interferon-α and chemokines, leading to the activation of a Th1 immune response. Therefore, synthetic equivalents...
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| Pubblicato in: | Hum Vaccin Immunother |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4514178/ https://ncbi.nlm.nih.gov/pubmed/25751765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2014.1004033 |
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