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CpG oligodeoxynucleotides as mucosal adjuvants

Bacterial DNA comprising palindromic sequences and containing unmethylated CpG is recognized by toll-like receptor 9 of plasmacytoid dendritic cells (pDCs) and induces the production of interferon-α and chemokines, leading to the activation of a Th1 immune response. Therefore, synthetic equivalents...

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Dades bibliogràfiques
Publicat a:Hum Vaccin Immunother
Autors principals: Iho, Sumiko, Maeyama, Jun-ichi, Suzuki, Fumiko
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514178/
https://ncbi.nlm.nih.gov/pubmed/25751765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2014.1004033
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