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A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-immunization Protection against Inhaled Anthrax in Monkeys()

Nanoparticulate delivery systems for vaccine adjuvants, designed to enhance targeting of secondary lymphoid organs and activation of APCs, have shown substantial promise for enhanced immunopotentiation. We investigated the adjuvant activity of synthetic oligonucleotides containing CpG-rich motifs (C...

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Bibliografiske detaljer
Udgivet i:J Immunol
Main Authors: Kachura, Melissa A., Hickle, Colin, Kell, Sariah A., Sathe, Atul, Calacsan, Carlo, Kiwan, Radwan, Hall, Brian, Milley, Robert, Ott, Gary, Coffman, Robert L., Kanzler, Holger, Campbell, John D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684989/
https://ncbi.nlm.nih.gov/pubmed/26608924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501903
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