Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components

Individual recombinant components of pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes (PDHc, OGDHc) of human and Escherichia coli (E. coli) origin were expressed and purified from E. coli with optimized protocols. The four multienzyme complexes were each reconstituted under optimal co...

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Bibliografiska uppgifter
I publikationen:Free Radic Biol Med
Huvudupphovsmän: Ambrus, Attila, Nemeria, Natalia S., Torocsik, Beata, Tretter, Laszlo, Nilsson, Mattias, Jordan, Frank, Adam-Vizi, Vera
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684775/
https://ncbi.nlm.nih.gov/pubmed/26456061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2015.10.001
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