A multipronged approach unravels unprecedented protein–protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

The human 2-oxoglutaric acid dehydrogenase complex (hOGDHc) plays a pivotal role in the tricarboxylic acid (TCA) cycle, and its diminished activity is associated with neurodegenerative diseases. The hOGDHc comprises three components, hE1o, hE2o, and hE3, and we recently reported functionally active...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Zhou, Jieyu, Yang, Luying, Ozohanics, Oliver, Zhang, Xu, Wang, Junjie, Ambrus, Attila, Arjunan, Palaniappa, Brukh, Roman, Nemeria, Natalia S., Furey, William, Jordan, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2018
Onderwerpen:
Enzymology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302161/
https://ncbi.nlm.nih.gov/pubmed/30323066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005432
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